I saw this and thought of RetroMacCast...
This is a quick blurb about the computer used on the Lunar Excursion Module (LEM) betwen 1969 and 1972 on http://dvorak.org/blog
A Brief Look At The Computer That Helped With The Lunar Landing
From the posting:
It’s cycle time was 1 Mhz, 11 instructions. It had 1K of 16 bit words of erasable (RAM) core memory and 12K of read-only memory (ROM). The ROM held the “Colossus 249″ flight control software. There were no disks or tapes in the flight system.